{"product_id":"ara-290","title":"ARA-290","description":"\u003cp\u003e\u003cspan\u003eARA-290\u003c\/span\u003e\u003cspan\u003e (also known as Cibinetide or Pyroglutamate Helix B Surface Peptide) is an 11-amino-acid synthetic peptide derived from the erythropoietin (EPO) structure, designed specifically to target tissue protection and inflammation without stimulating red blood cell production.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eKey Mechanisms \u0026amp; Characteristics\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003eSelective IRR Agonism:\u003c\/span\u003e\u003cspan\u003e Binds exclusively to the Innate Repair Receptor (IRR)—a heterodimer of EPO receptor and CD131—which triggers anti-inflammatory, anti-apoptotic, and regenerative signaling pathways.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003eNo Hematopoietic Activity:\u003c\/span\u003e\u003cspan\u003e Lacks binding affinity for the homodimeric EPO receptor, meaning it does not increase red blood cell counts, hematocrit, or blood viscosity.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003eNerve Fiber Regeneration:\u003c\/span\u003e\u003cspan\u003e Researched extensively for its ability to reduce neuropathic pain and promote small fiber nerve density regeneration.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003eAnti-Inflammatory Cascade:\u003c\/span\u003e\u003cspan\u003e Inhibits pro-inflammatory cytokine cascades (TNF-α, IL-6, IL-1β) at injury sites.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003enot for human consumption. Refrigeration after reconstituting. \u003c\/span\u003e\u003c\/p\u003e","brand":"PEPPERS EDMONTON 🇨🇦","offers":[{"title":"Default Title","offer_id":48103850934324,"sku":null,"price":80.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0774\/1711\/9796\/files\/17701ACC-56DF-46A9-B9DB-FC8A5CFC7039.jpg?v=1785971218","url":"https:\/\/peppersedmonton.ca\/products\/ara-290","provider":"PEPPERS EDMONTON 🇨🇦","version":"1.0","type":"link"}