{"product_id":"ghkcu-100","title":"GHKCU 100","description":"\u003cp\u003e\u003cspan\u003eGHK-Cu\u003c\/span\u003e\u003cspan\u003e (Copper Tripeptide-1) is a naturally occurring human tripeptide composed of \u003c\/span\u003e\u003cspan\u003eGlycine, Histidine, and Lysine\u003c\/span\u003e\u003cspan\u003e bound to a copper ion (\u003c\/span\u003e\u003cspan\u003eCu^{2+}\u003c\/span\u003e\u003cspan\u003e). First discovered in human plasma in 1973, GHK-Cu levels decline significantly with age—dropping from roughly 200 ng\/mL at age 20 to around 80 ng\/mL by age 60.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eIt is widely regarded as the gold standard for \u003c\/span\u003e\u003cspan\u003eskin remodeling, tissue repair, anti-aging, and extracellular matrix (ECM) regeneration\u003c\/span\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003ePrimary Mechanisms of Action\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eGHK-Cu acts as a signal peptide and dynamic feedback regulator for connective tissue repair and gene expression:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1. \u003c\/span\u003e\u003cspan\u003eCollagen \u0026amp; Elastin Synthesis:\u003c\/span\u003e\u003cspan\u003e Stimulates fibroblasts to produce Type I and Type III collagen, elastin, and glycosaminoglycans (like hyaluronic acid), restoring skin density, firmness, and elasticity.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2. \u003c\/span\u003e\u003cspan\u003eTissue Remodeling \u0026amp; Scar Reduction:\u003c\/span\u003e\u003cspan\u003e Regulates both metalloproteinases (MMPs) and their inhibitors (TIMPs). This dual action breaks down damaged, cross-linked collagen (old scar tissue) and replaces it with healthy, organized extracellular matrix.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3. \u003c\/span\u003e\u003cspan\u003eGene Expression Modulation:\u003c\/span\u003e\u003cspan\u003e Studies indicate GHK-Cu resets the expression of over 4,000 human genes, upregulating tissue repair and antioxidant defense genes while downregulating inflammatory genes.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e4. \u003c\/span\u003e\u003cspan\u003eAngiogenesis \u0026amp; Wound Healing:\u003c\/span\u003e\u003cspan\u003e Delivers ionic copper necessary for lysyl oxidase activity and accelerates blood vessel growth to supply oxygen and nutrients to damaged tissue.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003enot for human consumption, keeping in refrigerator after reconstitution.\u003c\/p\u003e","brand":"PEPPERS EDMONTON 🇨🇦","offers":[{"title":"Default Title","offer_id":48092250406964,"sku":null,"price":70.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0774\/1711\/9796\/files\/710A4433-2B95-4E93-93A5-94EDDE296138.jpg?v=1785633139","url":"https:\/\/peppersedmonton.ca\/products\/ghkcu-100","provider":"PEPPERS EDMONTON 🇨🇦","version":"1.0","type":"link"}