{"product_id":"ghkcu-50","title":"GHKCU 50","description":"\u003cp\u003e\u003cspan\u003eGHK-Cu\u003c\/span\u003e\u003cspan\u003e (Copper Tripeptide-1) is a naturally occurring human plasma \u003c\/span\u003e\u003cspan\u003etripeptide\u003c\/span\u003e\u003cspan\u003e (\u003c\/span\u003e\u003cspan\u003eGlycyl-L-histidyl-L-lysine\u003c\/span\u003e\u003cspan\u003e) bound to a copper(II) ion.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eFirst isolated from human blood plasma in 1973 by Dr. Loren Pickart, GHK-Cu levels naturally decline with age—dropping from roughly 200 ng\/mL at age 20 to around 80 ng\/mL by age 60. It functions as a powerful signal peptide that regulates gene expression to drive tissue remodeling, wound healing, and anti-aging pathways.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003ePrimary Key Mechanisms\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003eExtracellular Matrix Remodeling:\u003c\/span\u003e\u003cspan\u003e GHK-Cu stimulates the synthesis of \u003c\/span\u003e\u003cspan\u003etype I and type III collagen\u003c\/span\u003e\u003cspan\u003e, elastin, and glycosaminoglycans (like hyaluronic acid), restoring structural firmness and density to skin and connective tissues.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003eGene Expression Regulation:\u003c\/span\u003e\u003cspan\u003e Studies show GHK modulates over 4,000 human genes—upregulating tissue repair and antioxidant genes while downregulating pro-inflammatory and fibrotic pathways.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003eCopper Transport \u0026amp; Delivery:\u003c\/span\u003e\u003cspan\u003e Serves as a bio-available carrier, delivering copper (\u003c\/span\u003e\u003cspan\u003e\\text{Cu}^{2+}\u003c\/span\u003e\u003cspan\u003e) directly into cells where it acts as an essential cofactor for key enzymes like \u003c\/span\u003e\u003cspan\u003elysyl oxidase\u003c\/span\u003e\u003cspan\u003e (cross-linking collagen\/elastin) and \u003c\/span\u003e\u003cspan\u003esuperoxide dismutase (SOD)\u003c\/span\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003eAngiogenesis \u0026amp; Microcirculation:\u003c\/span\u003e\u003cspan\u003e Promotes new capillary growth and vessel integrity at injury or treatment sites, improving oxygenation and nutrient delivery.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003eAntioxidant \u0026amp; Anti-Inflammatory:\u003c\/span\u003e\u003cspan\u003e Neutralizes free radicals and suppresses pro-inflammatory cytokines (such as IL-6 and TNF-\u003c\/span\u003e\u003cspan\u003e\\alpha\u003c\/span\u003e\u003cspan\u003e), protecting damaged tissues from oxidative degradation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003enot for human consumption refrigerate after reconstitution\u003c\/p\u003e","brand":"PEPPERS EDMONTON 🇨🇦","offers":[{"title":"Default Title","offer_id":48092051079220,"sku":null,"price":50.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0774\/1711\/9796\/files\/F5A86F5B-EFE6-4C17-A752-C4BC39075531.jpg?v=1785610742","url":"https:\/\/peppersedmonton.ca\/products\/ghkcu-50","provider":"PEPPERS EDMONTON 🇨🇦","version":"1.0","type":"link"}