{"product_id":"igf-1lr3-1","title":"IGF-1LR3 1","description":"\u003cp\u003e\u003cspan\u003eIGF-1 LR3\u003c\/span\u003e\u003cspan\u003e (Insulin-like Growth Factor-1 Long Arg3) is a synthetic, highly potent analogue of human IGF-1. While native IGF-1 consists of 70 amino acids, IGF-1 LR3 is modified with an added \u003c\/span\u003e\u003cspan\u003e13-amino-acid N-terminal extension\u003c\/span\u003e\u003cspan\u003e and a substitution of \u003c\/span\u003e\u003cspan\u003eArginine for Glutamic acid at position 3\u003c\/span\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThese molecular modifications give IGF-1 LR3 a significantly extended active half-life compared to standard IGF-1, making it one of the most studied anabolic peptides for tissue growth and hyperplasia.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eWhat Makes \"Long R3\" Different?\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eNative IGF-1 produced in the body is quickly bound and neutralized by \u003c\/span\u003e\u003cspan\u003eIGF Binding Proteins (IGFBP)\u003c\/span\u003e\u003cspan\u003e, resulting in a brief active half-life of roughly \u003c\/span\u003e\u003cspan\u003e20 to 30 minutes\u003c\/span\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1. \u003c\/span\u003e\u003cspan\u003eEvasion of Binding Proteins:\u003c\/span\u003e\u003cspan\u003e The structural modifications in IGF-1 LR3 drastically reduce its affinity for IGFBPs.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2. \u003c\/span\u003e\u003cspan\u003eExtended Half-Life:\u003c\/span\u003e\u003cspan\u003e Because it floats freely without being deactivated by binding proteins, its biological half-life stretches to \u003c\/span\u003e\u003cspan\u003e20–30 hours\u003c\/span\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3. \u003c\/span\u003e\u003cspan\u003eSystemic Potency:\u003c\/span\u003e\u003cspan\u003e This extended half-life allows the peptide to circulate systemically, continually binding to cell surface IGF-1 receptors throughout the body.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003enot for human consumption keep in the refrigerator after reconstitution\u003c\/p\u003e","brand":"PEPPERS EDMONTON 🇨🇦","offers":[{"title":"Default Title","offer_id":48092245295156,"sku":null,"price":100.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0774\/1711\/9796\/files\/802E4344-93F6-408C-AFB7-27C894BBEF80.jpg?v=1785632806","url":"https:\/\/peppersedmonton.ca\/products\/igf-1lr3-1","provider":"PEPPERS EDMONTON 🇨🇦","version":"1.0","type":"link"}