{"product_id":"kpv-10","title":"KPV 10","description":"\u003cp\u003e\u003cspan\u003eKPV\u003c\/span\u003e\u003cspan\u003e is a potent synthetic \u003c\/span\u003e\u003cspan\u003etripeptide\u003c\/span\u003e\u003cspan\u003e (\u003c\/span\u003e\u003cspan\u003eLysine-Proline-Valine\u003c\/span\u003e\u003cspan\u003e) representing the C-terminal fragment of the naturally occurring peptide hormone \u003c\/span\u003e\u003cspan\u003e\\alpha\u003c\/span\u003e\u003cspan\u003e-MSH\u003c\/span\u003e\u003cspan\u003e (\u003c\/span\u003e\u003cspan\u003e\\alpha\u003c\/span\u003e\u003cspan\u003e-melanocyte-stimulating hormone).\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eDespite consisting of only three amino acids, KPV retains the powerful anti-inflammatory and immunomodulatory properties of full-length \u003c\/span\u003e\u003cspan\u003e\\alpha\u003c\/span\u003e\u003cspan\u003e-MSH, but \u003c\/span\u003e\u003cspan\u003ewithout activating melanocortin receptors\u003c\/span\u003e\u003cspan\u003e (meaning it produces zero skin tanning or pigmentation effects).\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003ePrimary Key Mechanisms\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003eInhibition of NF-\u003c\/span\u003e\u003cspan\u003e\\kappa\u003c\/span\u003e\u003cspan\u003eB: KPV enters cells and prevents the translocation of \u003c\/span\u003e\u003cspan\u003eNuclear Factor kappa B (NF-\u003c\/span\u003e\u003cspan\u003e\\kappa\u003c\/span\u003e\u003cspan\u003eB)\u003c\/span\u003e\u003cspan\u003e into the nucleus. Because NF-\u003c\/span\u003e\u003cspan\u003e\\kappa\u003c\/span\u003e\u003cspan\u003eB is the master switch for inflammatory signaling, blocking it directly suppresses the production of pro-inflammatory cytokines (such as IL-1$\\beta$, IL-6, and TNF-\u003c\/span\u003e\u003cspan\u003e\\alpha\u003c\/span\u003e\u003cspan\u003e).\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003eDirect Antimicrobial Activity:\u003c\/span\u003e\u003cspan\u003e Demonstrates intrinsic antimicrobial, antibacterial, and antifungal properties—particularly against pathogens like \u003c\/span\u003e\u003cspan\u003eCandida albicans\u003c\/span\u003e\u003cspan\u003e and \u003c\/span\u003e\u003cspan\u003eStaphylococcus aureus\u003c\/span\u003e\u003cspan\u003e—by disrupting microbial cell membranes.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003eWound Healing \u0026amp; Anti-Fibrotic Effects:\u003c\/span\u003e\u003cspan\u003e Regulates collagen production in dermal and mucosal wounds, promoting tissue repair while reducing the formation of thick, fibrotic scar tissue.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003eGastrointestinal Epithelial Preservation:\u003c\/span\u003e\u003cspan\u003e Protects and repairs the tight junctions in the intestinal mucosa, reducing intestinal permeability (\"leaky gut\") and calming mucosal inflammation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003enot for human consumption keep in refrigerator after reconstituting. \u003c\/p\u003e","brand":"PEPPERS EDMONTON 🇨🇦","offers":[{"title":"Default Title","offer_id":48092058943540,"sku":null,"price":50.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0774\/1711\/9796\/files\/259CA325-E9E4-421A-8731-E8E3AFA36487.jpg?v=1785611390","url":"https:\/\/peppersedmonton.ca\/products\/kpv-10","provider":"PEPPERS EDMONTON 🇨🇦","version":"1.0","type":"link"}