{"product_id":"melanotan-2-10","title":"Melanotan 2 10","description":"\u003cp\u003e\u003cspan\u003eMelanotan 2\u003c\/span\u003e\u003cspan\u003e (also known as \u003c\/span\u003e\u003cspan\u003eMT-2\u003c\/span\u003e\u003cspan\u003e) is a synthetic \u003c\/span\u003e\u003cspan\u003ecyclic heptapeptide\u003c\/span\u003e\u003cspan\u003e (\u003c\/span\u003e\u003cspan\u003eAc-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂\u003c\/span\u003e\u003cspan\u003e).\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eLike Melanotan 1, it is an analogue of the naturally occurring peptide hormone \u003c\/span\u003e\u003cspan\u003e\\alpha\u003c\/span\u003e\u003cspan\u003e-MSH\u003c\/span\u003e\u003cspan\u003e (\u003c\/span\u003e\u003cspan\u003e\\alpha\u003c\/span\u003e\u003cspan\u003e-melanocyte-stimulating hormone). However, its cyclic structure grants it a much higher potency, a longer biological half-life, and broad affinity across multiple central and peripheral melanocortin receptors.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003ePrimary Key Mechanisms\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003eBroad Melanocortin Receptor Agonism:\u003c\/span\u003e\u003cspan\u003e Unlike MT-1 (which primarily targets MC1R in the skin), MT-2 non-selectively stimulates \u003c\/span\u003e\u003cspan\u003eMC1R, MC3R, MC4R, and MC5R\u003c\/span\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003eMelanogenesis (MC1R):\u003c\/span\u003e\u003cspan\u003e Binds heavily to MC1R on epidermal melanocytes, triggering tyrosinase activity to convert pheomelanin into photoprotective \u003c\/span\u003e\u003cspan\u003eeumelanin\u003c\/span\u003e\u003cspan\u003e (dark brown pigment), producing rapid skin tanning with minimal UV exposure.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003ePro-Erectile \u0026amp; Sexual Function (MC3R\/MC4R):\u003c\/span\u003e\u003cspan\u003e Crosses the blood-brain barrier to bind central MC3R and MC4R in the hypothalamus, inducing central nervous system-mediated sexual arousal and erectile responses independent of vascular pathways.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003eAppetite Suppression (MC4R):\u003c\/span\u003e\u003cspan\u003e Central MC4R activation signals satiety in the brain, leading to a notable reduction in appetite and reduced caloric intake.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003erefrigerate after reconstitution not for human consumption.\u003c\/p\u003e","brand":"PEPPERS EDMONTON 🇨🇦","offers":[{"title":"Default Title","offer_id":48092050849844,"sku":null,"price":50.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0774\/1711\/9796\/files\/5256450D-2946-4621-81F1-194475CAA053.jpg?v=1785610623","url":"https:\/\/peppersedmonton.ca\/products\/melanotan-2-10","provider":"PEPPERS EDMONTON 🇨🇦","version":"1.0","type":"link"}