{"product_id":"mots-c-40","title":"MOTS-C 40","description":"\u003cp\u003e\u003cspan\u003e* hydrophobic Peptide do not keep in the fridge keep in a cool dark place* \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eMOTS-c\u003c\/span\u003e\u003cspan\u003e (Mitochondrial Open Reading Frame of the 12S rRNA type-c) is a 16-amino-acid peptide encoded not by nuclear DNA, but directly within the \u003c\/span\u003e\u003cspan\u003emitochondrial genome\u003c\/span\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eClassified as a \u003c\/span\u003e\u003cspan\u003eMitochondrial-Derived Peptide (MDP)\u003c\/span\u003e\u003cspan\u003e, MOTS-c acts as a signaling hormone that regulates metabolic homeostasis, cellular energy balance, and exercise mimetic signaling throughout the body.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eWhat Makes MOTS-c Unique?\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eMost peptides used in longevity and body composition protocols target hormone receptors or growth factor pathways. MOTS-c is distinct because it operates directly on \u003c\/span\u003e\u003cspan\u003emetabolic pathways and nuclear gene expression\u003c\/span\u003e\u003cspan\u003e:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1. \u003c\/span\u003e\u003cspan\u003eRetrograde Signaling:\u003c\/span\u003e\u003cspan\u003e When cellular energy stress occurs, MOTS-c translocates from the mitochondria to the cell nucleus, directly influencing nuclear DNA expression to restore metabolic equilibrium.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2. \u003c\/span\u003e\u003cspan\u003eExercise Mimetic Properties:\u003c\/span\u003e\u003cspan\u003e It activates key pathways (such as AMPK) that are naturally triggered during intense cardiovascular endurance or resistance training.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3. \u003c\/span\u003e\u003cspan\u003eMitochondrial Genome Origin:\u003c\/span\u003e\u003cspan\u003e It is part of a newly discovered class of bioactive peptides produced directly by the cell's powerhouses.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003enot for human consumption. \u003c\/p\u003e","brand":"PEPPERS EDMONTON 🇨🇦","offers":[{"title":"Default Title","offer_id":48092245786676,"sku":null,"price":120.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0774\/1711\/9796\/files\/DC08052A-7313-45FB-B890-9716D64A37D7.jpg?v=1785632904","url":"https:\/\/peppersedmonton.ca\/products\/mots-c-40","provider":"PEPPERS EDMONTON 🇨🇦","version":"1.0","type":"link"}