{"product_id":"nad-1000","title":"NAD + 1000","description":"\u003cp\u003e\u003cspan\u003eNAD+ (Nicotinamide Adenine Dinucleotide)\u003c\/span\u003e\u003cspan\u003e is an essential coenzyme found in all living cells, serving as a critical electron transporter in cellular metabolism and a necessary substrate for enzymes involved in DNA repair and longevity pathways.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eKey Mechanisms \u0026amp; Characteristics\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003eRedox Reactions (Energy Production):\u003c\/span\u003e\u003cspan\u003e Functions as an electron carrier, converting back and forth between NAD+ (oxidized) and NADH (reduced) to drive ATP production within mitochondrial oxidative phosphorylation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003eSirtuin Activation:\u003c\/span\u003e\u003cspan\u003e Acts as a required co-substrate for sirtuins (SIRT1–SIRT7), enzymes that regulate chromatin remodeling, mitochondrial biogenesis, oxidative stress resistance, and gene expression.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003ePARP Signaling \u0026amp; DNA Repair:\u003c\/span\u003e\u003cspan\u003e Consumed directly by Poly(ADP-ribose) polymerases (PARPs) to detect and initiate repairs on damaged cellular DNA.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003eAge-Dependent Decline:\u003c\/span\u003e\u003cspan\u003e Endogenous levels drop significantly with age, stress, and metabolic strain, leading to impaired mitochondrial function and reduced cellular repair capacity.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003enot for human consumption. For research only. \u003cbr\u003ekeep refrigerated\u003c\/span\u003e\u003c\/p\u003e","brand":"PEPPERS EDMONTON 🇨🇦","offers":[{"title":"Default Title","offer_id":48103851294772,"sku":null,"price":95.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0774\/1711\/9796\/files\/040AE27B-9E86-46B3-A6A8-4B5F496C42B3.jpg?v=1785971345","url":"https:\/\/peppersedmonton.ca\/products\/nad-1000","provider":"PEPPERS EDMONTON 🇨🇦","version":"1.0","type":"link"}