{"product_id":"pt-141-10","title":"PT-141 10","description":"\u003cp\u003e\u003cspan\u003ePT-141\u003c\/span\u003e\u003cspan\u003e (brand name \u003c\/span\u003e\u003cspan\u003eVyleesi\u003c\/span\u003e\u003cspan\u003e, generic name \u003c\/span\u003e\u003cspan\u003eBremelanotide\u003c\/span\u003e\u003cspan\u003e) is a synthetic \u003c\/span\u003e\u003cspan\u003ecyclic heptapeptide\u003c\/span\u003e\u003cspan\u003e (\u003c\/span\u003e\u003cspan\u003eAc-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH\u003c\/span\u003e\u003cspan\u003e).\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eOriginally developed as a metabolite derivative of Melanotan 2 (MT-2), scientists isolated PT-141 specifically to harness its pro-sexual signaling while stripping away the N-terminal amide group, removing MT-2’s severe skin-tanning properties. It is a targeted therapy designed for the treatment of sexual dysfunction in both men and women.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003ePrimary Key Mechanisms\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003eCentral Nervous System Activation:\u003c\/span\u003e\u003cspan\u003e Unlike traditional vascular medications (like PDE5 inhibitors\/Viagra) that act peripherally on blood vessels, PT-141 acts directly on the central nervous system by crossing the blood-brain barrier.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003eMelanocortin Receptor Agonism:\u003c\/span\u003e\u003cspan\u003e It functions primarily as a potent agonist at \u003c\/span\u003e\u003cspan\u003eMC3R and MC4R\u003c\/span\u003e\u003cspan\u003e (melanocortin 3 and 4 receptors) in the hypothalamus—the region of the brain regulating motivation, desire, and sexual behavior.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003eDopaminergic Pathways:\u003c\/span\u003e\u003cspan\u003e Binding to hypothalamic MC4R triggers downstream release of \u003c\/span\u003e\u003cspan\u003edopamine\u003c\/span\u003e\u003cspan\u003e, directly heightening sexual desire, arousal, and intimacy-seeking behavior.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003eMinimization of Melanogenesis:\u003c\/span\u003e\u003cspan\u003e By removing the structural components that drive heavy MC1R activation, PT-141 produces minimal to no skin darkening compared to its parent compound, MT-2.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003erefrigerate after reconstitution not for human consumption.\u003c\/p\u003e","brand":"PEPPERS EDMONTON 🇨🇦","offers":[{"title":"Default Title","offer_id":48092051734580,"sku":null,"price":50.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0774\/1711\/9796\/files\/1FA3C992-4EBC-4396-AE7B-57B236AF8612.jpg?v=1785610985","url":"https:\/\/peppersedmonton.ca\/products\/pt-141-10","provider":"PEPPERS EDMONTON 🇨🇦","version":"1.0","type":"link"}