{"product_id":"tesamorlin-20","title":"Tesamorlin 20","description":"\u003cp\u003e\u003cspan\u003eTesamorelin\u003c\/span\u003e\u003cspan\u003e (brand name \u003c\/span\u003e\u003cspan\u003eEgrifta\u003c\/span\u003e\u003cspan\u003e) is a synthetic \u003c\/span\u003e\u003cspan\u003eGrowth Hormone-Releasing Hormone (GHRH) analogue\u003c\/span\u003e\u003cspan\u003e consisting of \u003c\/span\u003e\u003cspan\u003e44 amino acids\u003c\/span\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eIt is engineered with a hexenoyl moiety attached to the N-terminus of human GHRH, making it significantly more resistant to rapid enzymatic degradation by dipeptidyl peptidase-4 (DPP-4) compared to natural GHRH.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003ePrimary Key Mechanisms\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003ePulsatile GH Secretion:\u003c\/span\u003e\u003cspan\u003e Tesamorelin binds directly to GHRH receptors on somatotroph cells in the anterior pituitary gland, triggering the synthesis and pulsatile release of endogenous \u003c\/span\u003e\u003cspan\u003eGrowth Hormone (GH)\u003c\/span\u003e\u003cspan\u003e without shutting down natural pituitary function.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003eUpregulation of IGF-1:\u003c\/span\u003e\u003cspan\u003e Increased GH prompts the liver and peripheral tissues to produce \u003c\/span\u003e\u003cspan\u003eInsulin-like Growth Factor 1 (IGF-1)\u003c\/span\u003e\u003cspan\u003e, driving metabolic signaling, cellular repair, and protein synthesis.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003eTargeted Visceral Lipolysis:\u003c\/span\u003e\u003cspan\u003e Tesamorelin selectively stimulates lipolysis (fat breakdown) in \u003c\/span\u003e\u003cspan\u003evisceral adipose tissue (VAT)\u003c\/span\u003e\u003cspan\u003e—the deep, dangerous abdominal fat surrounding internal organs—with minimal effect on subcutaneous fat.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003eMetabolic \u0026amp; Lipid Modulation:\u003c\/span\u003e\u003cspan\u003e By reducing visceral fat depots, it improves systemic lipid profiles, lowering triglycerides and non-HDL cholesterol.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003erefrigerate after reconstitution not for human consumption.\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/p\u003e","brand":"PEPPERS EDMONTON 🇨🇦","offers":[{"title":"Default Title","offer_id":48092050391092,"sku":null,"price":120.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0774\/1711\/9796\/files\/06CDF0E2-F253-46BA-937A-EB30FAED29FE.jpg?v=1785610353","url":"https:\/\/peppersedmonton.ca\/products\/tesamorlin-20","provider":"PEPPERS EDMONTON 🇨🇦","version":"1.0","type":"link"}