{"product_id":"tirzepatide-30","title":"Tirzepatide 30","description":"\u003cp\u003e\u003cspan\u003eTirzepatide\u003c\/span\u003e\u003cspan\u003e (brand names \u003c\/span\u003e\u003cspan\u003eMounjaro\u003c\/span\u003e\u003cspan\u003e and \u003c\/span\u003e\u003cspan\u003eZepbound\u003c\/span\u003e\u003cspan\u003e) is a synthetic \u003c\/span\u003e\u003cspan\u003e39-amino-acid peptide\u003c\/span\u003e\u003cspan\u003e engineered as a \u003c\/span\u003e\u003cspan\u003edual GIP and GLP-1 receptor agonist\u003c\/span\u003e\u003cspan\u003e.\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eUnlike single-acting incretin mimetics (such as semaglutide, which only targets GLP-1), tirzepatide acts as a \"twincretin\". It combines the sequences of \u003c\/span\u003e\u003cspan\u003eGIP\u003c\/span\u003e\u003cspan\u003e (\u003c\/span\u003e\u003cspan\u003eglucose-dependent insulinotropic polypeptide\u003c\/span\u003e\u003cspan\u003e) and \u003c\/span\u003e\u003cspan\u003eGLP-1\u003c\/span\u003e\u003cspan\u003e (\u003c\/span\u003e\u003cspan\u003eglucagon-like peptide-1\u003c\/span\u003e\u003cspan\u003e) into a single unimolecular backbone, yielding synergistic effects on metabolic control, insulin sensitivity, and substantial body weight reduction.\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003ePrimary Key Mechanisms\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003eDual Receptor Agonism (GIP + GLP-1):\u003c\/span\u003e\u003cspan\u003e Activates both GIP and GLP-1 receptors in the pancreas, central nervous system, and adipose tissue. The added GIP component complements GLP-1 to enhance lipid metabolism, improve nutrient partitioning, and drive greater appetite suppression.\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003eGlucose-Dependent Insulin Secretion:\u003c\/span\u003e\u003cspan\u003e Stimulates pancreatic beta cells to release insulin primarily when blood glucose levels are elevated, lowering postprandial blood sugar while minimizing the risk of hypoglycemia.\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003eGlucagon Suppression:\u003c\/span\u003e\u003cspan\u003e Suppresses inappropriate liver glucagon release during high blood sugar episodes, stopping excess hepatic glucose production.\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003eDelayed Gastric Emptying:\u003c\/span\u003e\u003cspan\u003e Slows the rate at which the stomach empties into the small intestine, prolonging post-meal fullness and blunting blood sugar spikes.\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003eCentral Appetite \u0026amp; Reward Regulation:\u003c\/span\u003e\u003cspan\u003e Crosses hypothalamic signaling pathways to decrease hunger, increase satiety signaling, and quiet central food cravings.\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003cbr\u003e\u003cbr\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003erefrigerate after reconstitution not for human  Consumption\u003c\/p\u003e","brand":"PEPPERS EDMONTON 🇨🇦","offers":[{"title":"Default Title","offer_id":48092057272372,"sku":null,"price":120.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0774\/1711\/9796\/files\/350D41DD-FF28-48DE-8D75-1602C688B115.jpg?v=1785611109","url":"https:\/\/peppersedmonton.ca\/products\/tirzepatide-30","provider":"PEPPERS EDMONTON 🇨🇦","version":"1.0","type":"link"}