MOTS-C 40

* hydrophobic Peptide do not keep in the fridge keep in a cool dark place* 

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA type-c) is a 16-amino-acid peptide encoded not by nuclear DNA, but directly within the mitochondrial genome.

Classified as a Mitochondrial-Derived Peptide (MDP), MOTS-c acts as a signaling hormone that regulates metabolic homeostasis, cellular energy balance, and exercise mimetic signaling throughout the body.

What Makes MOTS-c Unique?

Most peptides used in longevity and body composition protocols target hormone receptors or growth factor pathways. MOTS-c is distinct because it operates directly on metabolic pathways and nuclear gene expression:

1. Retrograde Signaling: When cellular energy stress occurs, MOTS-c translocates from the mitochondria to the cell nucleus, directly influencing nuclear DNA expression to restore metabolic equilibrium.

2. Exercise Mimetic Properties: It activates key pathways (such as AMPK) that are naturally triggered during intense cardiovascular endurance or resistance training.

3. Mitochondrial Genome Origin: It is part of a newly discovered class of bioactive peptides produced directly by the cell's powerhouses.

not for human consumption.