NAD + 1000
NAD+ (Nicotinamide Adenine Dinucleotide) is an essential coenzyme found in all living cells, serving as a critical electron transporter in cellular metabolism and a necessary substrate for enzymes involved in DNA repair and longevity pathways.
Key Mechanisms & Characteristics
Β Redox Reactions (Energy Production): Functions as an electron carrier, converting back and forth between NAD+ (oxidized) and NADH (reduced) to drive ATP production within mitochondrial oxidative phosphorylation.
Β Sirtuin Activation: Acts as a required co-substrate for sirtuins (SIRT1βSIRT7), enzymes that regulate chromatin remodeling, mitochondrial biogenesis, oxidative stress resistance, and gene expression.
Β PARP Signaling & DNA Repair: Consumed directly by Poly(ADP-ribose) polymerases (PARPs) to detect and initiate repairs on damaged cellular DNA.
Β Age-Dependent Decline: Endogenous levels drop significantly with age, stress, and metabolic strain, leading to impaired mitochondrial function and reduced cellular repair capacity.
not for human consumption. For research only.Β
keep refrigerated