NAD+ 500

NAD+ (Nicotinamide Adenine Dinucleotide) is technically a coenzyme rather than a peptide, though it is frequently grouped into peptide therapy protocols due to its complementary role in cellular repair, longevity, and mitochondrial optimization.

It is a critical pyridine nucleotide found in every living cell, where it serves as a central engine for mitochondrial energy production and DNA repair. Endogenous NAD+ levels decline significantly with age—dropping by up to 50% by middle age—leading to metabolic slowdown, decreased cellular energy, and impaired cellular repair.

Primary Key Mechanisms

 Mitochondrial Energy Production (ATP Synthesis): NAD+ acts as an essential electron carrier in cellular respiration. It shuttles high-energy electrons through the Krebs cycle and electron transport chain, converting nutrients into usable energy (ATP).

 Sirtuin Activation (Longevity Genes): NAD+ is an obligatory substrate for sirtuins (SIRT1–SIRT7)—a family of signaling proteins that regulate epigenetic modification, cellular aging, metabolic homeostasis, and stress resistance.

 DNA Repair (PARP Pathway): It fuels PARP (poly-ADP-ribose polymerase) enzymes, which detect and repair single-strand DNA breaks caused by oxidative stress, UV radiation, and environmental toxins.

 Neurotransmitter & Cognitive Support: Facilitates cellular communication in the central nervous system, helping regulate neuroinflammation, synaptic integrity, and mental clarity.

refrigerate after reconstitution not for human consumption.