SS31 10

SS-31 (also known as Elamipretide, MTP-131, or Bendavia) is a synthetic tetrapeptide (D-Arg-Dmt-Lys-Phe-NH₂) engineered specifically to target and restore mitochondrial dysfunction.

Unlike traditional antioxidants that scavenge free radicals generally throughout the cell, SS-31 selectively concentrates in the inner mitochondrial membrane (IMM), addressing cellular energy production at its source.

Primary Key Mechanisms

 Cardiolipin Binding: SS-31 selectively binds to cardiolipin, a unique phospholipid exclusive to the inner mitochondrial membrane. Cardiolipin is critical for maintaining mitochondrial structure, cristae curvature, and electron transport chain (ETC) function.

 Restoring ATP Production: By stabilizing cardiolipin, SS-31 optimizes the assembly and function of the supercomplexes within the electron transport chain. This improves mitochondrial respiration and increases ATP (adenosine triphosphate) output.

 Targeted ROS Reduction: It prevents the electron leakage that generates excessive Reactive Oxygen Species (ROS) without disrupting normal, healthy cell signaling radicals.

 Structural Preservation: Preserves mitochondrial morphology and prevents the opening of the mitochondrial permeability transition pore (mPTP), protecting cells from stress-induced apoptosis (cell death).

refrigerate after reconstitution not for human consumption.